Sildenafil PAH: Sildenafil in the Treatment of Pulmonary Hypertension

Most people only know the Erectile Dysfunction side of Sildenafil. This drug, Sildenafil, was first introduced by Pfizer in the market in 1997 as the answer to ED. Viagra was an instant hit, getting worldwide popularity overnight. But little do most people know, Pfizer has also manufactured another Sildenafil product as a treatment for a different health condition. Revatio was the name of this product and it’s not as well-known as its older brother even though its also Sildenafil. Having lower dosages compared to Viagra, Revatio is just perfect for Pulmonary Hypertension because the body doesn’t require large amounts of Sildenafil to be relieved from this ailment.

Sildenafil, commonly known as Viagra, is a drug that inhibits the Phosphodiesterase type 5 enzyme in the body. As it inhibits this enzyme, the body will now relax the muscles surrounding the blood vessels which will temporarily dilate them, enabling these blood passageways to carry more blood to different parts of the body and improve the overall blood circulation.

Pulmonary Arterial Hypertension is a rare disease that only occurs in 15 to 50 instances in a million. People aged 20 to 60 is the common age bracket that this condition affects. Its occurrence is more common in women than men and is also linked with obesity in most of the cases. This disease takes place in the pulmonary arteries where the blood flows from the heart to the lungs. PAH occurs when these arteries grow narrow and constricted, preventing the heart from supplying the lungs with sufficient amounts of blood that it needs. By taking Sildenafil, these arteries will now become dilated, allowing easy blood flow and better blood circulation in the body.

This condition rarely occurs as the only disease in the body as it usually stems as a complication from other illnesses such as heart disease, lung disease, liver disease, and HIV infection. Those who have a family history with this condition are also more likely to develop the disease according to studies. People who also use illegal drugs and diet medications are more susceptible to develop Pulmonary Hypertension. People who also live at high altitudes are at risk for developing this disease.

Sildenafil Pulmonary Hypertension Dose

Only small doses of Sildenafil are needed in providing relief to patients experiencing this condition. Revatio’s Sildenafil dosages are only 20mg, 10mg, and 5mg.

Revatio IV 10mg Label

Revatio IV 10mg Label

The dosage amounts to be taken should depend on the dosage recommendation of the physician, no more and no less. Unlike Viagra that should only be taken once every 24 hours and only when needed, Pulmonary Hypertension requires that small doses of Sildenafil be taken every day, three times a day, with intervals of 4 hours in between doses. 20mg is the maximum dose per intake and the patient should also follow the doctor’s instructions concerning the foods and drugs that should not be taken with Sildenafil to avoid any health risks and to maximize the effect of the medication.

Sildenafil for Pulmonary Hypertension in Neonates

The adults are not the only ones at risk of having Pulmonary Hypertension. Newborn babies (or neonates) are also prone to this condition. When infants are born, there is a high level of pressure in the blood vessels of their lungs and this blood pressure only normalizes once the normal breathing of the infant is established. But this is not always the case because, in some babies, this transition does not occur immediately. As a result, their blood pressure remains high and this prevents the proper amount of blood from getting to the lungs to supply it with oxygen. If left unchecked, this could lead to other health complications to the newborn infant because of the lack of oxygen that the other organs inside the body needs.

With precise dosage carefully administered by a physician, Sildenafil can also be used to treat infants. Sildenafil will help to dilate the narrow arteries and blood vessels in the infant’s lungs, allowing them to have normal levels of blood pressure and ensuring a fluid blood circulation inside their bodies. This will now enable their lungs to get the right amount of oxygen from the blood, helping them breathe properly.

Sildenafil Secondary Pulmonary Hypertension

This type of Pulmonary Hypertension is the development or a form of complication from other diseases that the patient already has. Chronic Obstructive Pulmonary Diseases (COPD) such as chronic bronchitis, emphysema, asthma, and bronchiectasis may cause Pulmonary Hypertension if left unchecked. Congenital heart disorders can also lead to secondary Pulmonary Hypertension if not treated properly.

Lungs, heart, and the pulmonary arteries

Lungs, heart, and the pulmonary arteries

But if the person has already developed this condition, Sildenafil will still be able to help. Since Sildenafil won’t be affecting their other conditions apart from the arteries that have become rigid and narrow, the dilation of these blood passageways will give relief to the patient and will allow them to perform normal physical tasks. Strenuous physical activities are no longer recommended for people with PAH for the reason that it could be fatal for them with their condition.


Sildenafil is not only used for people who have ED but this drug is also a life-saver for the ones experiencing Pulmonary Arterial Hypertension. Pfizer has manufactured its Sildenafil brand Revatio specifically for patients who have PAH because this condition only requires small dosages of Sildenafil compared to ED. Sildenafil can provide relief to patients with all types of Pulmonary Hypertension for it dilates the narrow arteries allowing the blood to flow freely from the heart to the lungs unrestricted. Sildenafil can also be used for infants with PAH as it helps in normalizing the high blood pressures that they commonly experience as their lungs adjust to breathing air for the first time. if you need Sildenafil for the management of PAH, consider checking our Catalog of Verified Online Pharmacies.